Wayne Cawthorne

This study identifies dysregulated epithelial cell death signaling in inflammatory bowel disease, showing it persists during remission despite therapy.

This study shows that necroptosis in keratinocytes promotes differentiation and slows wound healing by preserving barrier integrity, suggesting it can be modulated to enhance tissue repair.

The paper develops automated immunohistochemistry protocols to detect necroptotic pathway proteins in mouse and human tissues, revealing heterogeneity and disease-related changes in expression.