Tracey L. Schultz

This paper identifies TgATG2 as a key component of the Toxoplasma gondii autophagy machinery required for bradyzoite survival and cyst persistence.

This study shows that Salmonella Typhi uses asparaginase to deplete asparagine, activating the GCN2 kinase and the integrated stress response in murine macrophages, which enhances bacterial killing.

This study shows that Toxoplasma gondii's PLP1 protein drives cytokine release syndrome by inducing dysregulated immune responses, leading to lethal inflammation during acute infection.

This study identifies TgPROP1 as essential for autophagy and chronic infection of Toxoplasma gondii bradyzoites, while TgPROP2 is not involved in bradyzoite autophagy.

This paper shows type I interferon coordinates immunometabolic checkpoints during Staphylococcal infection by regulating metabolic and inflammatory programs in macrophages.

This study identifies eIF1.2 as a regulator of Toxoplasma gondii differentiation by controlling the translation of key bradyzoite factors.

This study shows that Candida albicans activates IRE1 in macrophages through non-canonical mechanisms, enhancing fungicidal activity by promoting phagolysosomal fusion.

This study identifies TgAAT1, a putative arginine transporter in Toxoplasma gondii, which localizes to the PLVAC and is essential for extracellular survival and bradyzoite differentiation.