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This study examines how acute resistance exercise affects endocannabinoid levels and psychological states in trained and untrained adults, finding decreases in endocannabinoids and improvements in mood.

This study shows that acute ceramide formation via NSmase is essential for NO signaling in human microvascular endothelium, with distinct mechanisms in healthy individuals and CAD patients.

This study shows itaconate stabilizes CPT1a to enhance lipid utilization during inflammation, revealing a novel metabolic role in modulating fatty acid oxidation during sepsis.

This study investigates CO2 detection in earthworms using an exudate assay and pharmacological inhibitors, identifying carbonic anhydrase and sodium channels as key players.

This study identifies perivascular excitation tunnelling (PVET) as a novel mechanism causing reperfusion arrhythmias and shows that two-step reperfusion can prevent it in rabbit and pig hearts.

This study shows that protecting the vascular barrier by targeting Cx43 and Panx1 channels reduces atrial fibrillation episodes and preserves cardiac nanostructure.

This study shows that middle-infrared radiation improves sleep by enhancing blood circulation and reducing homocysteine and T-cell levels, linking cardiometabolic function to sleep quality.

This study identifies structural and metabolic changes in human heart failure using SBF-SEM and metabolomic analyses.

This study shows aging impairs muscle regeneration by promoting fibro/fatty degeneration and inhibiting inflammation resolution through reduced Periostin in fibro/adipogenic progenitors.

This study shows that 2-hydroxybutyrate (2HB) produced during exercise inhibits branched-chain aminotransferases, leading to metabolic changes that enhance oxidative capacity.

The paper evaluates the use of the genetically encoded calcium indicator Salsa6F in cardiac applications, comparing it to Fluo-4AM and demonstrating its utility in measuring calcium transients in cardiomyocytes and heart preparations.

The paper shows that loss of neuronatin increases susceptibility of SERCA to thermal inactivation in murine skeletal muscle.

This study investigates the role of S1PR2 in mouse retinal light responses and finds altered light responses and structural changes in S1PR2 knockout mice.

This study assesses tag retention and post-surgical mortality in Atlantic salmon post-smolts and finds high tag expulsion rates and weak negative correlation with tag:body mass ratio.

This study shows that extracellular sodium concentration directly regulates FGF23 synthesis in osteoblast-like cells and links this regulation to NFAT5 expression, with implications for disease states like hyponatremia.

This paper applies independent component analysis to dynamic oxygen-enhanced MRI to extract oxygen-induced signals and assess lung function differences between smokers and non-smokers.

This study investigates the effects of repeated methamphetamine exposure on zebrafish cardiac function, revealing decreased heart rate, increased heart rate variability, and fibrotic changes.

Vasodilators stimulate TRPV4 channels, leading to calcium-dependent activation of nearby TMEM16A channels in endothelial cells to produce arterial hyperpolarization, vasodilation, and reduced blood pressure.

This study shows that endothelial EGFR signaling is crucial for functional hyperemia, as its deletion impairs cerebral blood flow responses to neuronal activity.

This study investigates how nitric oxide modulates calcium handling and arrhythmias via S-nitrosylation of CaMKIIδ at specific sites during β-adrenergic signaling.