Author

A. Aher

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 4 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

A. Akhmanova· 2 shared L. Urnavicius· 2 shared T. M. Kapoor· 2 shared A. Xue· 1 shared B. T. Chait· 1 shared C.-Y. Chen· 1 shared D. Rai· 1 shared E. A. Katrukha· 1 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

A. Akhmanova

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Structure of the γ-tubulin ring complex-capped microtubule

A. Aher, L. Urnavicius, A. Xue, K. Neselu, T. Kapoor

The paper reports the structure of the γ-tubulin ring complex-capped microtubule, revealing how it nucleates and stabilizes 13-protofilament microtubules.

bioRxiv · Nov 20, 2023Biochemistry

Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function

M. Wieczorek, S.-C. Ti, L. Urnavicius, K. R. Molloy, A. Aher, B. T. Chait, T. M. Kapoor

This paper reconstitutes the human γ-TuRC and analyzes its structure and function, showing that the lumenal bridge is essential for microtubule nucleation.

bioRxiv · Sep 21, 2020Biochemistry

Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase

K. J. Mickolajczyk, P. M. M. Shelton, M. Grasso, X. Cao, S. R. Warrington, A. Aher, S. Liu, T. M. Kapoor

This study investigates the force-dependent unwinding activity of SARS-CoV-2 nsp13 helicase using optical tweezers, revealing increased unwinding frequency, processivity, and velocity under destabilizing force.

bioRxiv · Jul 31, 2020Biophysics

CLASP mediates microtubule repair by promoting tubulin incorporation into damaged lattices

A. Aher, D. Rai, L. Schaedel, J. Gaillard, K. John, L. Blanchoin, M. Thery, A. Akhmanova

This study shows CLASP2 promotes microtubule lattice repair by facilitating tubulin incorporation into damaged sites and stabilizing partial protofilaments.

bioRxiv · Oct 17, 2019Cell Biology

Mechanisms of motor-independent membrane remodeling driven by dynamic microtubules

R. Rodriguez-Garcia, V. A. Volkov, C.-Y. Chen, E. A. Katrukha, N. Olieric, A. Aher, I. Grigoriev, M. Preciado Lopez, M. O. Steinmetz, L. C. Kapitein, G. Koenderink, M. Dogterom, A. Akhmanova

This study reconstitutes membrane tubulation using dynamic microtubules and proteins, revealing three motor-independent mechanisms for membrane remodeling.

bioRxiv · Aug 8, 2019Cell Biology

Exocyst subcomplex functions in autophagosome biogenesis by regulating Atg9 trafficking

S. S. Rajput, S. Chinchwadkar, A. Aher, S. Matheshwaran, R. Manjithaya

The paper investigates the role of Exocyst subcomplexes in autophagosome biogenesis by regulating Atg9 trafficking during autophagy.

bioRxiv · Apr 24, 2018Cell Biology