K. John

Whole genome sequencing-based multi-locus association mapping for kernel iron, zinc and protein content in groundnut

This study uses whole genome sequencing and GWAS to identify genetic markers associated with kernel iron, zinc, and protein content in groundnut, aiding in breeding for improved nutritional traits.

Human long noncoding RNA, VILMIR, is induced by major respiratory viral infections and modulates the host interferon response

This study identifies VILMIR, a novel lncRNA upregulated by respiratory viral infections and IFN-β, which modulates the host interferon response.

Geometry and cell wall mechanics guide early pollen tube growth in Arabidopsis thaliana

This study investigates how geometry and cell wall mechanics guide early pollen tube growth in Arabidopsis thaliana, showing that WT papilla cells direct growth while ktn1-5 mutants allow free movement along geodesics.

A fast-slow trait continuum at the level of entire communities

The paper shows that slow and fast functional strategies manifest at the ecosystem level, driven by disturbance and resource availability in grassland communities.

Development of allosteric, selective cyclin-dependent kinase 2 (CDK2) inhibitors that are negatively cooperative with cyclin binding and show potential as contraceptive agents

This paper develops high-affinity, structurally confirmed allosteric CDK2 inhibitors that show negative cooperativity with cyclin binding and demonstrate contraceptive potential in mouse testicular explants.

Substrate stiffness impacts early biofilm formation by modulating Pseudomonas aeruginosa twitching motility

This study shows that substrate stiffness affects Pseudomonas aeruginosa biofilm formation by altering twitching motility and phenotypic expression.

Measuring salivary cortisol in wild carnivores

This study develops a non-invasive method to measure salivary cortisol in wild spotted hyenas and finds a bimodal daily rhythm, social rank effects, and aggression-related cortisol changes.

CLASP mediates microtubule repair by promoting tubulin incorporation into damaged lattices

This study shows CLASP2 promotes microtubule lattice repair by facilitating tubulin incorporation into damaged sites and stabilizing partial protofilaments.

Self-repair protects microtubules from their destruction by molecular motors

The paper investigates how molecular motors affect microtubule stability and discovers a self-repair mechanism that counteracts motor-induced damage.

Lattice defects induce microtubule self-renewal

This study shows that microtubules can exchange dimers along their shaft, requiring lattice defects, enabling self-renewal and potential regulation of signaling and structural changes.