Author

A. Berchuck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 5

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 5 Organism:human· 5 Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

R. Whitaker· 2 shared S. K. Murphy· 2 shared Z. Huang· 2 shared A. A. Hippen· 1 shared A. Campbell· 1 shared A. K. Shelton· 1 shared A. Nixon· 1 shared B. K. Dalley· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersCancer Biology

R. Whitaker

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Author profile →

5 papers

Recent·Most cited

Molecular subtypes of high grade serous ovarian cancer across racial groups and gene expression platforms

N. R. Davidson, M. E. Barnard, A. A. Hippen, A. Campbell, C. Johnson, G. P. Way, B. K. Dalley, A. Berchuck, L. A. Salas, L. C. Peres, J. R. Marks, J. M. Schildkraut, C. S. Greene, J. A. Doherty

This study identifies molecular subtypes of high-grade serous ovarian cancer across racial groups and gene expression platforms, finding similar subtype-specific survival rates despite differences in subtype prevalence.

bioRxiv · Nov 1, 2023Cancer Biology

Periostin facilitates ovarian cancer recurrence by enhancing cancer stemness

Z. Huang, O. Byrd, S. Tan, B. Knight, G. Lo, L. Taylor, A. Berchuck, S. K. Murphy

This study shows that periostin promotes ovarian cancer recurrence by enhancing cancer stemness and chemoresistance through TME interactions.

bioRxiv · Mar 30, 2023Cancer Biology

G6PD Inhibition Sensitizes Ovarian Cancer Cells to Oxidative Stress in the Metastatic Omental Microenvironment

S. Bose, Q. Huang, Y. Ma, L. Wang, G. O. Rivera, Y. Ouyang, R. Whitaker, R. A. Gibson, C. D. Kontos, A. Berchuck, R. Previs, X. Shen

This study shows G6PD inhibition increases oxidative stress and reduces omental metastases in ovarian cancer.

bioRxiv · Apr 20, 2022Cancer Biology

Reciprocal epigenetic Sox2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer

Z. SHONIBARE, M. Monavarian, K. O'Connell, D. Altomare, A. K. Shelton, S. Mehta, R. Jaskula-Sztul, R. Phaeton, M. D. Starr, R. Whitaker, A. Berchuck, A. Nixon, R. C. Arend, N. Y. Lee, C. R. Miller, , K. Mythreye

This study identifies Sox2 as a key node regulated by opposing TGF-β superfamily signals, impacting anoikis resistance and metastasis in ovarian cancer.

bioRxiv · Jan 11, 2022Cancer Biology

Targeting dormant ovarian cancer cells in vitro and in an in vivo model of platinum resistance

Z. Huang, E. Kondoh, Z. Visco, T. Baba, N. Matsumura, E. Dolan, R. S. Whitaker, I. Konishi, S. Fujii, A. Berchuck, S. K. Murphy

This study characterizes ovarian cancer spheroid phenotypes, identifies gene expression profiles linked to spheroid formation, and evaluates therapeutic responses of spheroids to various agents.

bioRxiv · Jul 26, 2019Cancer Biology