N. Y. Lee

This study identifies an alternative splice variant of Drp1 in ovarian cancer that promotes metastasis and chemoresistance by altering mitochondrial dynamics.

This study identifies heparan sulfate modifications as critical for betaglycan ectodomain shedding, which regulates TGF-β signaling and has clinical implications in ovarian cancer.

The paper shows TAK1 activates TAT1 to acetylate microtubules, promoting ER tubulation and cell survival by downregulating BOK.

The paper introduces a new V allele naming scheme and genotype inference method for adaptive immune receptor sequencing, validated with genomic long read data and implemented in an R package.

The paper shows that autolysosomal exocytosis of lipid-protein particles protects neurons from ferroptosis by removing peroxidated lipids and iron.

This study identifies Sox2 as a key node regulated by opposing TGF-β superfamily signals, impacting anoikis resistance and metastasis in ovarian cancer.

The paper identifies Mfn2-S249 as a phosphoregulatory switch controlling mitochondrial fusion dynamics through TAK1-mediated phosphorylation, affecting mitochondrial morphology and energy homeostasis.

This paper develops a framework for rapid bacterial species identification using 3D quantitative phase imaging and artificial neural networks, achieving 99.9% accuracy with single colony-forming units.

This study shows that SIRT3 activation is required for ovarian cancer cell survival and metastasis by regulating mitochondrial antioxidant defenses and metabolic changes during detachment.