Author

A. Bhushan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1

Frequent Co-Authors

B. Willard· 2 shared C. Tam· 2 shared J. K. Chan· 2 shared Y. Sun· 2 shared A. A. Joshi· 1 shared A. Shah· 1 shared B. A. Lone· 1 shared C. Wang· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 9 mutual co-author links

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2 shared papersCell Biology

B. Willard

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Epithelial cytokeratin 6a restricts secretory autophagy of proinflammatory cytokines by interacting with Sec16A

A. Bhushan, J. K. Chan, Y. Sun, F. Ghiamati, J. S. Crabb, G.-F. Jang, B. Willard, J. W. Crabb, C. Tam

This study shows that K6a restricts secretory autophagy of proinflammatory cytokines by interacting with Sec16A, reducing cytokine secretion in corneal epithelial cells.

bioRxiv · Jan 4, 2024 · PreprintCell Biology

Keratin 6a attenuates Toll-like receptor-triggered proinflammatory response in corneal epithelial cells by suppressing ELKS/IKKϵ-dependent activation of NF-κB

J. K. Chan, Y. Sun, A. Bhushan, B. Willard, C. Tam

This study shows that keratin 6a suppresses TLR-triggered inflammation in corneal epithelial cells by modulating ELKS/IKKε-dependent NF-κB activation, preventing excessive cytokine and chemokine production.

bioRxiv · Oct 24, 2023 · PreprintImmunology

Trilliumosides A-B, two novel steroidal saponins isolated from Rhizomes of Trillium govanianum as potent anticancer agents targeting apoptosis in A-549 cancer cell line.

P. Gupta, B. A. Lone, M. Tabassum, A. Bhushan, U. Dhiman, D. Rani, P. N. Gupta, D. M. Mondhe, S. Gairola

This study isolates two novel steroidal saponins from Trillium govanianum rhizomes and demonstrates their potent anticancer activity against A-549 cells through apoptosis induction.

bioRxiv · Apr 17, 2023Cancer Biology

A Novel Standalone Microfluidic Device for Local Control of Oxygen Tension for Intestinal-Bacteria Interactions

C. Wang, T. Dang, J. Baste, A. A. Joshi, A. Bhushan

This paper introduces a microfluidic device that creates a dual-oxygen environment for studying intestinal epithelial and bacterial interactions without external chambers.

bioRxiv · May 22, 2020Bioengineering

BET proteins are required for transcriptional activation of the senescent beta cell secretome in Type 1 Diabetes

P. J. Thompson, A. Shah, C.-C. Apostolopolou, A. Bhushan

This study identifies BET proteins as key regulators of the senescent beta cell secretome in Type 1 Diabetes, showing their role in activating SASP and offering a potential therapeutic target.

bioRxiv · Aug 15, 2019Physiology