Cancer BiologybioRxiv
ISGylation drives basal breast tumour progression by promoting EGFR recycling and Akt signalling
A. von Kriegsheim, A. Bolado-Carrancio, M. Muir…·P. Caswell
This study shows that ISGylation promotes breast tumour progression by enhancing EGFR recycling and Akt signalling, acting as a driver rather than just a marker of cancer.
DOI 10.1038/s41388-021-02017-8