Author

C. Semple

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Bolado-Carrancio· 1 shared A. Ewing· 1 shared A. Navaei· 1 shared A. von Kriegsheim· 1 shared D. Zocco· 1 shared I. Passalacqua· 1 shared J. Nabhan· 1 shared K. Luther· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. Bolado-Carrancio

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2 papers

Recent·Most cited

Scalable Production and Purification of Engineered ARRDC1-Mediated Microvesicles in a HEK293 Suspension Cell System

K. Luther, A. Navaei, L. Gens, C. Semple, P. Moharil, I. Passalacqua, K. Vyas, Q. Wang, S.-L. Liu, L. Sun, S. Ramaswamy, D. Zocco, J. Nabhan

This study develops scalable methods to produce and purify engineered ARRDC1-mediated microvesicles (ARMMs) for gene therapy delivery, showing efficient production and in vivo biodistribution.

bioRxiv · May 14, 2024Bioengineering

ISGylation drives basal breast tumour progression by promoting EGFR recycling and Akt signalling

A. von Kriegsheim, A. Bolado-Carrancio, M. Muir, A. Ewing, K. Macleod, W. Gallagher, L. Nguyen, N. O. Carragher, C. Semple, V. Brunton, P. Caswell

This study shows that ISGylation promotes breast tumour progression by enhancing EGFR recycling and Akt signalling, acting as a driver rather than just a marker of cancer.

bioRxiv · Sep 12, 2019Cancer Biology