ImmunologybioRxiv
Monocytes and macrophages, targets of SARS-CoV-2: the clue for Covid-19 immunoparalysis
A. Boumaza, L. Gay, S. Mezouar…·J.-L. Mege
This study shows SARS-CoV-2 infects monocytes and macrophages, inducing immunoregulatory cytokine secretion and M2-type transcriptional changes, leading to immunoparalysis in Covid-19 patients.
DOI 10.1093/infdis/jiab044