Author

D. Raoult

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 14 Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 13 Organism:human· 9 Research Focus:cell type annotation· 7 Assay:proteomics· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Assay:DNA methylation· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

B. La Scola· 8 shared A. Levasseur· 6 shared E. Chabriere· 5 shared P. Colson· 5 shared J. Delerce· 3 shared J. Y. Bou Khalil· 3 shared L. Pinault· 3 shared P. Pontarotti· 3 shared

Activity by Year

2017-2023 · peak 7/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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Curved chords = mutual co-authorship

8 shared papersMicrobiology

B. La Scola

Mutual co-authors in cluster

Author profile →

16 papers

Recent·Most cited

Resuscitating Sleeping Beauties: reviving a six-hundred-year-old amoeba and endosymbiont.

I. Hasni, M. L. Tall, M. Le Bailly, P. Colson, A. Levasseur, D. Raoult, B. La Scola, M. Drancourt

This study revives a 600-year-old Acanthamoeba castellanii strain and its endosymbiont from coprolites, revealing their genomic features and survival mechanisms.

bioRxiv · Sep 22, 2023 · PreprintMicrobiology

Role of SARS-CoV-2 mutations in the evolution of the COVID-19 pandemic

P. Colson, H. Chaudet, J. Delerce, P. Pontarotti, A. Levasseur, J. Fantini, B. La Scola, C. A. Devaux, D. Raoult

The paper analyzes SARS-CoV-2 mutations across 61,397 genomes to identify 'hyperfertile' mutations that spread widely, finding most did not predict new epidemic forms, with some in non-coding regions and stop codons.

bioRxiv · May 1, 2023Microbiology

Adapted protocol for Saccharibacteria co-cultivation: two new members join the club of Candidate Phyla radiation

A. Ibrahim, M. Maatouk, A. Rajaonison, R. Zgheib, G. Haddad, J. Y. Bou Khalil, D. Raoult, F. Bittar

This paper develops a co-cultivation protocol for Saccharibacteria, successfully isolating two new species and providing tools for their quantification and study.

bioRxiv · Jul 23, 2021Microbiology

Stool serology: development of a non-invasive immunological method for the detection of Enterovirus-specific antibodies in Congo gorilla faeces

Y. Sereme, S. M. Zarza, H. Medkour, I. Amona, F. Fenollar, J. Akiana, S. Mezouar, N. Orain, J. Vitte, B. Davoust, D. Raoult, O. Mediannikov

The paper develops a non-invasive method to detect Enterovirus-specific antibodies in gorilla faeces, finding specific antibodies in 4/16 gorilla samples and 2/3 human samples.

bioRxiv · Nov 28, 2020Microbiology

Tricarboxylic acid cycle and proton gradient in Pandoravirus massiliensis: Is it still a virus?

S. Aherfi, D. BRAHIM BELHAOUARI, L. Pinault, J.-P. Baudoin, P. Decloquement, J. Abrahao, P. Colson, A. LEVASSEUR, D. C. Lamb, E. Chabriere, D. Raoult, B. LA SCOLA

This study identifies functional enzymes of the tricarboxylic acid cycle in Pandoravirus massiliensis, suggesting it may possess energy production capabilities and challenging traditional virus definitions.

bioRxiv · Sep 21, 2020Microbiology

Monocytes and macrophages, targets of SARS-CoV-2: the clue for Covid-19 immunoparalysis

A. Boumaza, L. Gay, S. Mezouar, A. B. Diallo, M. Michel, B. Desnues, D. Raoult, B. LA SCOLA, P. Halfon, J. Vitte, D. Olive, J.-L. Mege

This study shows SARS-CoV-2 infects monocytes and macrophages, inducing immunoregulatory cytokine secretion and M2-type transcriptional changes, leading to immunoparalysis in Covid-19 patients.

bioRxiv · Sep 17, 2020Immunology

Dual RNase and β-lactamase activity of a single enzyme encoded in most Archaea

S. M. Diene, L. Pinault, N. Armstrong, V. Keshri, S. Khelaifia, E. Chabriere, G. Caetano-Anolles, J.-M. Rolain, P. Pontarotti, D. Raoult

The paper identifies dual RNase and β-lactamase activity in an archaeal enzyme, challenging previous annotations and highlighting functional specialization over time.

bioRxiv · Jun 10, 2020 · PreprintMicrobiology

High speed large scale automated isolation of SARS-CoV-2 from clinical samples using miniaturized co-culture coupled with high content screening

R. Francis, M. Le Bideau, P. Jardot, C. Grimaldier, D. Raoult, J. Y. Bou Khalil, B. La Scola

This paper presents a high-content screening method for rapid and automated isolation of SARS-CoV-2 from clinical samples, achieving comparable isolation rates to traditional methods but with faster results and reduced contamination risks.

bioRxiv · May 14, 2020Microbiology

High Content Screening, a reliable system for Coxiella burnetii isolation from clinical samples

R. Francis, M. Mioulane, M. Le Bideau, M.-C. Mati, P.-E. Fournier, D. Raoult, J. Y. Bou Khalil, B. La Scola

This paper develops a high content screening (HCS) method for isolating Coxiella burnetii from clinical samples, showing higher sensitivity and efficiency compared to traditional shell-vial assays.

bioRxiv · Dec 17, 2019Microbiology

Lactobacillus reuteri: direct passage from ingested yogurts to urine microbiota

J. C. Lagier, F. Mekhalif, V. Merhej, H. Chaudet, J. Delerce, A. Levasseur, D. Raoult

The paper shows that Lactobacillus reuteri from yogurt can pass into urine after consumption, colonizing it in some individuals.

bioRxiv · Dec 11, 2019 · PreprintMicrobiology

The dynamics and interactions of respiratory pathogen carriage among French pilgrims during the 2018 Hajj

V.-T. Hoang, T.-L. Dao, T. D. A. Ly, K. Belhouchat, K. L. Chaht, J. Gaudart, B. M. Mrenda, T. Drali, S. Yezli, B. Alotaibi, P.-E. Fournier, D. Raoult, P. Parola, V. Pommier de Santi, P. Gautret

This study tracks respiratory pathogen acquisition and interactions among French Hajj pilgrims, finding polymicrobial carriage and associations with lower respiratory tract infection symptoms.

Emerging Microbes & Infections · Nov 21, 2019Peer-reviewedMicrobiology

A metallo-beta-lactamase with both beta-lactamase and ribonuclease activity is linked with traduction in giant viruses

P. Colson, L. Pinault, S. Azza, N. Armstrong, E. Chabriere, B. La Scola, P. Pontarotti, D. Raoult

The paper identifies a metallo-beta-lactamase with dual beta-lactamase and ribonuclease activity in a giant virus and shows its RNase activity is not inhibited by common inhibitors.

bioRxiv · Oct 28, 2019 · PreprintMicrobiology

Transfer of CRISPR-like activity of MIMIVIRE into Bacteria

S. Azza, B. La Scola, A. Levasseur, P. Perrin, E. Chabriere, D. Raoult

The paper transfers the MIMIVIRE defence system from Mimiviruses to E. coli to eliminate a plasmid by targeting tetracycline resistance sequences.

bioRxiv · Jul 11, 2019 · PreprintMicrobiology

Dramatic HIV DNA degradation associated with spontaneous HIV suppression and disease-free outcome in a young seropositive woman following her infection

P. Colson, C. Dhiver, C. Tamalet, J. Delerce, O. Glazunova, M. Gaudin, A. Levasseur, D. Raoult

The paper identifies a HIV-1-seropositive woman who spontaneously suppressed HIV replication and found that dramatic HIV DNA degradation occurred, likely due to extrinsic factors like the gut microbiota.

bioRxiv · Jun 13, 2019Microbiology

Antioxidants maintain Butyrate production by Human Gut Clostridia in the presence of Oxygen

M. Million, N. Arsmtrong, S. Khelaifia, E. Guilhot, G. Dubourg, E. Chabriere, D. Raoult

The paper shows that antioxidants enable human gut Clostridia to produce butyrate aerobically, revealing an unexpected metabolic adaptation to oxidative stress.

bioRxiv · May 29, 2019 · PreprintMicrobiology

IRF4 haploinsufficiency in a family with Whipples disease

A. Guerin, G. Kerner, N. Marr, J. G. Markle, F. Fenollar, N. Wong, S. Boughorbel, D. T. Avery, C. Ma, S. Bougarn, M. Bouaziz, V. Beziat, E. Della Mina, T. Lazarovt, L. Worley, , J.-L. Casanova

This study identifies IRF4 haploinsufficiency as the genetic cause of Whipples disease in a family, showing age-dependent incomplete penetrance and chronic Tw carriage preceding disease onset.

bioRxiv · Oct 3, 2017Immunology