A. Chakrabarti

Microevolution of clade II isolates of Candida auris highlights multifaceted intra-clade heterogeneity in acquiring resistance towards amphotericin B

This study evolves two clade II Candida auris isolates to develop amphotericin B resistance, revealing distinct mechanisms and intra-clade heterogeneity in resistance acquisition.

Erythroid spectrin binding modulates peroxidase and catalase activity of heme proteins

This study shows that spectrin binding modulates peroxidase activity of hemoglobin and other heme proteins, with implications for oxidative damage in diseases like sickle cell disease.

Protein reservoirs of seeds are composites of amyloid and amyloid-like structures facilitating sustained release during germination and seedling growth

This study identifies amyloid and amyloid-like structures in plant seed storage protein bodies (SSPB) and demonstrates their role in controlling germination and seedling growth.

Spectrin Interactome under normal and HbE-disease conditions

The paper reports the first interactome of human erythroid spectrin and finds no change in interacting protein identity but altered abundance under HbE disease conditions, with increased redox and chaperone proteins.

Localizing the chaperone activity of erythroid spectrin

This study identifies hydrophobic surface patches on spectrin domains as the source of its chaperone activity, showing that all domains contribute equally to this function.