The Role of EBP50 in Regulating Endothelial-To-Mesenchymal Transition in Pulmonary Hypertension
A. Gorelova, M. Berman, M. Sharifi-Sanjani, A. Pulgarin Rocha, A. Alsuraimi, P. Riva, V. Negi, T. Bertero, D. Goncharov, T. Kudryashova, A. Dosunmu-Ogunbi, A. Rajaratnam, L. Harvey, M. Nouraie, J. Baust, , I. Al Ghouleh
This study shows EBP50 downregulation promotes EndMT in pulmonary hypertension by increasing Snail, Zeb1, and Slug expression, and mesenchymal markers, while reducing cell proliferation and barrier function.
bioRxiv · May 31, 2022 · PreprintCell Biology