Multi-parametric thrombus profiling microfluidics detects intensified biomechanical thrombogenesis associated with hypertension and aging
M. Din, S. Paul, S. Ullah, H. Yang, R.-G. Xu, N. A. Z. Abidin, A. Sun, Y. C. Chen, R. Gao, B. Chowdhury, F. Zhou, S. Rogers, M. Miller, A. Biswas, L. Hu, , Y. Chen
This paper introduces a microfluidics-based thrombus profiling assay that detects intensified biomechanical thrombogenesis in hypertension and aging, revealing a GPIb-integrin mechanosensing axis hyperactivity mechanism.
bioRxiv · Jun 11, 2024Bioengineering