Author

J. Dutra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

D. J. Hartigan-O'Connor· 2 shared J. D. Deere· 2 shared A. A. Ardeshir· 1 shared A. E. Patterson· 1 shared A. Jain· 1 shared A. M. Allen· 1 shared A. Verma· 1 shared A.-S. Archambault· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

D. J. Hartigan-O'Connor

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Author profile →

3 papers

Recent·Most cited

SIV clearance from neonatal macaques following transient CCR5 depletion

J. D. Deere, D. Merriam, K. M. Leggat, W. Lu, G. Mendez-Lagares, H. Kieu, J. Dutra, J. Fontaine, W. Lu, N. Chin, C. Chen, B. C.-T. Tran, J. Salinas, C. N. Miller, S. G. Deeks, , D. J. Hartigan-O'Connor

This study shows that targeted depletion of CCR5-expressing cells in neonatal macaques using bispecific antibodies can lead to long-term SIV remission and apparent cure.

bioRxiv · May 1, 2023 · PreprintImmunology

Inducing an oxidized redox-balance improves anti-tumor CD8+ T cell function

J. H. Oh, R. A. Cederberg, L. Bopp, E. Tanaka, T. Ser, S. Niyyati, A. E. Patterson, N. Amanat, J. Dutra, P. Ye, M. Clark, K. Ward-Hartstonge, A.-S. Archambault, J. Tsui, P. F. Lange, , R. I. K. Geltink

This study shows that inducing an oxidized redox balance in CD8+ T cells enhances their anti-tumor function in vivo through increased mitochondrial ROS.

bioRxiv · Mar 27, 2023 · PreprintImmunology

Early post-infection treatment of SARS-CoV-2 infected macaques with human convalescent plasma with high neutralizing activity reduces lung inflammation

K. K. A. Van Rompay, K. J. Olstad, R. L. Sammak, J. Dutra, J. K. Watanabe, J. L. Usachenko, R. Immareddy, J. W. Roh, A. Verma, Y. Shaan Lakshmanappa, B. Schmidt, C. Di Germanio, N. Rizvi, M. Stone, G. Simmons, , J. R. Reader

This study treats SARS-CoV-2 infected macaques with high-titer convalescent plasma, showing reduced lung inflammation without affecting virus replication.

bioRxiv · Sep 1, 2021 · PreprintImmunology