IL-1beta-induced epithelial cell and fibroblast transdifferentiation fuels neutrophil recruitment in chronic rhinosinusitis with nasal polyps
X. Xie, P. Wang, M. Jin, Y. Wang, L. Qi, C. Wu, S. Guo, C. Li, X. Zhang, Y. Yuan, X. Ma, F. Liu, W. Liu, H. Liu, C. Duan, , X. Feng
This study identifies IL-1beta-induced cell subsets that promote neutrophil recruitment in CRSwNP and shows IL-1beta inhibition reduces inflammation.
bioRxiv · Jan 28, 2024 · PreprintImmunology