Author

M. L. Bouxsein

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. J. Brooks· 2 shared M. N. Wein· 2 shared A. Brito· 1 shared A. Freund· 1 shared A. Lelis Carvalho· 1 shared A. Schlessinger· 1 shared A. Treyball· 1 shared A. Velduis-Vlug· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersPhysiology

D. J. Brooks

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Author profile →

4 papers

Recent·Most cited

Partial prevention of glucocorticoid-induced osteocyte deterioration with osteocrin gene therapy

C. M. Mazur, C. D. Castro Andrade, T. Sato, M. Bruce, M. L. Bouxsein, J. S. Wang, M. N. Wein

This study tests osteocrin gene therapy to prevent glucocorticoid-induced osteocyte damage in mice, finding partial protection against osteocyte death but not all skeletal effects.

bioRxiv · Nov 19, 2021 · PreprintPhysiology

Dual targeting of salt inducible kinases and CSF1R uncouples bone formation and bone resorption

C.-C. Tang, C. Castro, M. J. O'Meara, S.-H. Yoon, D. J. Brooks, M. L. Bouxsein, J. d. S. Martins, J. Wang, N. S. Gray, B. Misof, P. Roschger, S. Boulin, K. Klaushofer, A. Velduis-Vlug, Y. Vegting, , M. N. Wein

The paper shows that YKL-05-099, which inhibits SIKs and CSF1R, increases bone formation without increasing bone resorption in mice.

bioRxiv · Feb 26, 2021Physiology

Trpm8 modulates thermogenesis in a sex-dependent manner without influencing cold-induced bone loss

A. Lelis Carvalho, A. Treyball, D. J. Brooks, S. Costa, R. J. Neilson, M. R. Reagan, M. L. Bouxsein, k. Motyl

This study shows TRPM8 affects thermogenesis and bone density differently in males and females without impacting cold-induced bone loss.

bioRxiv · Mar 18, 2020 · PreprintPhysiology

Pharmacological inhibition of longevity regulator PAPP-A restrains mesenchymal stromal cell activity

M. Mohrin, J. Liu, J. Zavala-Solorio, S. Bhargava, J. M. Trumble, A. Brito, D. Hu, D. Brooks, M. L. Bouxsein, R. Baron, Y. Kutskova, A. Freund

This study shows that inhibiting PAPP-A reduces collagen and ECM gene expression and modulates mesenchymal stromal cell activity in mice.

bioRxiv · Feb 5, 2020 · PreprintPhysiology