Author

A. Brito

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. Aguilar· 2 shared B. Badie· 2 shared D. Alizadeh· 2 shared D. Wang· 2 shared J. R. Ostberg· 2 shared R. Starr· 2 shared S. J. Forman· 2 shared W.-C. Chang· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

B. Aguilar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Selective IL13Rα2-Targeted Functionality of IL13-Ligand CARs is Enhanced by Inclusion of 4-1BB Co-Stimulation

R. Starr, X. Yang, B. Aguilar, D. Gumber, S. Huard, D. Wang, W.-C. Chang, A. Brito, V. Chiu, J. R. Ostberg, B. Badie, S. J. Forman, D. Alizadeh, L. D. Wang, C. E. Brown

This study compares IL13-ligand CAR designs to determine how co-stimulation domains affect tumor selectivity and anti-tumor activity against glioblastoma.

bioRxiv · Mar 30, 2022 · PreprintImmunology

Pharmacological inhibition of longevity regulator PAPP-A restrains mesenchymal stromal cell activity

M. Mohrin, J. Liu, J. Zavala-Solorio, S. Bhargava, J. M. Trumble, A. Brito, D. Hu, D. Brooks, M. L. Bouxsein, R. Baron, Y. Kutskova, A. Freund

This study shows that inhibiting PAPP-A reduces collagen and ECM gene expression and modulates mesenchymal stromal cell activity in mice.

bioRxiv · Feb 5, 2020 · PreprintPhysiology

Chlorotoxin Redirects Chimeric Antigen Receptor T Cells for Specific and Effective Targeting of Glioblastoma

D. Wang, R. Starr, W.-C. Chang, B. Aguilar, D. Alizadeh, S. L. Wright, X. Yang, A. Brito, A. Sarkissian, J. R. Ostberg, Y. Shi, M. Gutova, K. Aboody, B. Badie, S. J. Forman, , C. Brown

This study develops a CAR T cell therapy using chlorotoxin to target glioblastoma with high specificity and potency, overcoming tumor heterogeneity challenges.

bioRxiv · Jan 24, 2020 · PreprintImmunology