Author

A. Hecker

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Cell Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

B. Petre· 2 shared C. Lorrain· 2 shared S. Duplessis· 2 shared A. Benard· 1 shared A. E. Kremer· 1 shared A. G. Pardo· 1 shared A. Jacobsen· 1 shared A. PADILLA· 1 shared

Activity by Year

2017-2020 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersMicrobiology

B. Petre

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections

A. Benard, A. Jacobsen, M. Brunner, C. Krautz, B. Klosch, I. Swierzy, E. Naschberger, T. Birkholz, I. Castellanos, D. Trufa, H. Sirbu, M. Vetter, A. E. Kremer, K. Hildner, A. Hecker, , G. F. Weber

The paper finds that low interleukin-3 levels predict increased severity and mortality in SARS-CoV-2 infections and shows IL-3 promotes antiviral pDC recruitment.

bioRxiv · Jul 2, 2020Immunology

Clathrin’s adaptor interaction sites are repurposed to stabilize microtubules during mitosis

A. Rondelet, Y.-C. Lin, D. Singh, A. T. Porfetye, H. C. Thakur, A. Hecker, P. Brinkert, N. Schmidt, S. Bendre, F. Mueller, P. O. Widlund, T. Bange, M. Hiller, I. R. Vetter, A. W. Bird

This paper identifies a novel role of clathrin in stabilizing microtubules during mitosis by repurposing its adaptor interaction sites to recruit GTSE1, which inhibits MCAK and supports chromosome congression.

bioRxiv · Aug 31, 2019Cell Biology

Structural genomic applied on the rust fungus Melampsora larici-populina reveals two candidate effector proteins adopting cystine-knot and nuclear transport factor 2-like protein folds

K. DEGUILLEN, C. Lorrain, P. Tsan, P. BARTHE, B. Petre, N. Saveleva, N. Rouhier, S. Duplessis, A. PADILLA, A. Hecker

The paper identifies two effector proteins from the rust fungus Melampsora larici-populina that adopt structural folds similar to knottin and nuclear transport factor 2-like proteins despite lacking sequence similarity.

bioRxiv · Aug 7, 2019Microbiology

Laccaria bicolor MiSSP8 is a small-secreted protein decisive for the establishment of the ectomycorrhizal symbiosis

C. Pellegrin, Y. Daguerre, J. Ruytinx, F. Guinet, M. Kemppainen, N. Frei dit Frey, V. Puech-Pages, A. HECKER, A. G. Pardo, F. MARTIN, C. Veneault-Fourrey

This study identifies MiSSP8 as a small-secreted protein essential for early ectomycorrhizal symbiosis by regulating hyphal aggregation and pseudoparenchyma formation in Laccaria bicolor.

bioRxiv · May 1, 2019Plant Biology

The rust fungus Melampsora larici-populina expresses a conserved genetic program and distinct sets of secreted protein genes during infection of its two host plants, larch and poplar

C. Lorrain, C. Marchal, S. Hacquard, C. Delaruelle, J. Petrowski, B. Petre, A. Hecker, P. Frey, S. Duplessis

This study compares the transcriptomes of the rust fungus Melampsora larici-populina during infection of larch and poplar, identifying host-specific secreted protein genes involved in host colonization.

bioRxiv · Dec 6, 2017Microbiology