Author

A. Jacobsen

Primary ORCID profile (0009-0000-2318-4672 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

A. JacobseniD1 paper

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

A. L. Samson· 2 shared C. Hall· 2 shared I. Wicks· 2 shared J. Hildebrand· 2 shared J. M. Murphy· 2 shared J. Silke· 2 shared K. R. Martin· 2 shared S. Chiou· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

A. L. Samson

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Author profile →

3 papers

Recent·Most cited

An immunohistochemical atlas of necroptotic pathway expression

S. Chiou, A. Al-Ani, Y. Pan, K. Patel, I. Kong, L. Whitehead, A. Light, S. Young, M. Barrios, C. Sargeant, P. Rajasekhar, L. Zhu, A. Hempel, A. Lin, J. Rickard, , A. L. Samson

The paper develops automated immunohistochemistry protocols to detect necroptotic pathway proteins in mouse and human tissues, revealing heterogeneity and disease-related changes in expression.

bioRxiv · Oct 31, 2023Cell Biology

A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation

S. E. Garnish, K. R. Martin, M. Kauppi, V. Jackson, R. Ambrose, V. V. Eng, S. Chiou, Y. Meng, D. Frank, E. C. Tovey Crutchfield, K. M. Patel, A. Jacobsen, G. Atkin-Smith, L. Di Rago, M. Doerflinger, , J. Hildebrand

The paper shows that a common MLKL polymorphism, S132P, enhances necroptotic activity in human cells and impairs recovery from infection in mice.

bioRxiv · Sep 8, 2022 · PreprintImmunology

Interleukin-3 is a predictive marker for severity and outcome during SARS-CoV-2 infections

A. Benard, A. Jacobsen, M. Brunner, C. Krautz, B. Klosch, I. Swierzy, E. Naschberger, T. Birkholz, I. Castellanos, D. Trufa, H. Sirbu, M. Vetter, A. E. Kremer, K. Hildner, A. Hecker, , G. F. Weber

The paper finds that low interleukin-3 levels predict increased severity and mortality in SARS-CoV-2 infections and shows IL-3 promotes antiviral pDC recruitment.

bioRxiv · Jul 2, 2020Immunology