Author

A. J. Covarrubias

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

A. Kale· 1 shared A. Oliveira Pisco· 1 shared B. Schilling· 1 shared C. Brenner· 1 shared C. D. Wiley· 1 shared E. Verdin· 1 shared H. G. Kasler· 1 shared I. Ben-Sahra· 1 shared

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2019-2019 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

A. Kale

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1 paper

Recent·Most cited

ImmunologybioRxivJul 31, 2019

Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ macrophages

A. J. Covarrubias, A. Kale, R. Perrone…·E. Verdin

This study identifies CD38+ macrophages as a driver of NAD decline during aging through inflammation linked to cellular senescence in metabolic tissues.

DOI 10.1038/s42255-020-00305-3

mousebulk RNA-seq

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