Author

A. Kale

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

B. Schilling· 2 shared J. Campisi· 2 shared N. Basisty· 2 shared A. D. Angın· 1 shared A. Holtz· 1 shared A. J. Covarrubias· 1 shared A. Oliveira Pisco· 1 shared C. Brenner· 1 shared

Activity by Year

2019-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersCell Biology

B. Schilling

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novel metabolic role for CD47 in pancreatic β-cell insulin secretion and islet transplant outcomes

K. Ghimire, A. Kale, J. Li, S. M. Julovi, P. O'Connell, S. T. Grey, W. J. Hawthorne, J. E. Gunton, N. M. Rogers

This study identifies CD47 as a regulator of insulin secretion and islet transplant outcomes, showing that its inhibition enhances insulin release and transplant efficiency.

bioRxiv · Jul 22, 2022Physiology

The Effects of Leukocyte- and Platelet-Rich Plasma (L-Prp) and Pure Platelet-Rich Plasma (P-Prp) an a Rat Endometriosis Model

A. D. Angın, i. gün, o. sakin, m. s. cıkman, Z. M. Pirimoglu, a. kale, k. basak, P. Kaygın, s. oguztüzün

This study evaluates the effects of leukocyte- and platelet-rich plasma (L-PRP) and pure platelet-rich plasma (P-PRP) on endometriosis in a rat model, finding no significant differences between groups.

bioRxiv · Oct 11, 2019 · PreprintPathology

A Proteomic Atlas of Senescence-Associated Secretomes for Aging Biomarker Development

N. Basisty, A. Kale, O. Jeon, C. Kuehnemann, T. Payne, C. Rao, A. Holtz, S. Shah, V. Sharma, L. Ferrucci, J. Campisi, B. Schilling

The paper develops a proteomic atlas of senescence-associated secretomes to identify aging biomarkers, finding that GDF15, STC1, and SERPINs correlate with age in human plasma.

bioRxiv · Aug 21, 2019Cell Biology

Aging-related inflammation driven by cellular senescence enhances NAD consumption via activation of CD38+ macrophages

A. J. Covarrubias, A. Kale, R. Perrone, J. A. Lopez-Dominguez, A. Oliveira Pisco, H. G. Kasler, M. S. Schmidt, C. D. Wiley, S. S. Iyer, N. Basisty, Q. Wu, R. Kwok, I. Heckenbach, K.-O. Shin, Y.-M. Lee, , E. Verdin

This study identifies CD38+ macrophages as a driver of NAD decline during aging through inflammation linked to cellular senescence in metabolic tissues.

bioRxiv · Jul 31, 2019Immunology