Author

A. Jennings

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:non-human primate· 1

Frequent Co-Authors

A. Sato· 1 shared C. J. Kirk· 1 shared C. Kalyanaraman· 1 shared C. Kambach· 1 shared C. Steegborn· 1 shared D. McMinn· 1 shared D. Tranter· 1 shared E. Lowe· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperBiophysics

A. Sato

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Signal peptide mimicry primes Sec61 for client-selective inhibition

S. Rehan, D. Tranter, P. P. Sharp, E. Lowe, J. Anderl, T. Muchamuel, V. Abrishami, S. Kuivanen, N. Wenzell, A. Jennings, C. Kalyanaraman, G. B. Craven, T. Strandin, M. Javanainen, O. Vapalahti, , V. Paavilainen

This study describes KZR-8445, a cyclic depsipeptide that selectively inhibits Sec61-mediated protein biogenesis by mimicking signal peptides, showing efficacy in a rheumatoid arthritis model.

bioRxiv · Jul 3, 2022Biochemistry

External fertilization is orchestrated by a pH-regulated soluble adenylyl cyclase controlling sperm motility and chemotaxis

H. G. Koerschen, H. Hamzeh, R. Pascal, L. Alvarez, W. Boenigk, N. Kaur, L. Levin, J. Buck, C. Kambach, M. Michino, A. Jennings, A. Sato, R. Seifert, T. Struenker, C. Steegborn, U. B. Kaupp

This paper identifies a pH-regulated soluble adenylyl cyclase in non-mammalian sperm that controls motility and chemotaxis, revealing evolutionary adaptations to aquatic environments.

bioRxiv · Jun 18, 2021 · PreprintBiophysics