Author

J. Buck

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

L. R. Levin· 2 shared N. Kaur· 2 shared A. A. Khrapitchev· 1 shared A. J. Verhoeven· 1 shared A. Jennings· 1 shared A. Sato· 1 shared C. Kambach· 1 shared C. Ritagliati· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPharmacology & Toxicology

L. R. Levin

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Imaging angiogenesis in an intracerebrally induced model of brain macrometastasis using αvβ3-targeted iron oxide microparticles

J. Buck, F. Perez-Balderas, N. Zarghami, V. A. Johanssen, A. A. Khrapitchev, J. R. Larkin, N. R. Sibson

This study evaluates the use of RGD-MPIO for imaging angiogenic vessels in brain metastases, finding reduced sensitivity due to endogenous iron and suggesting antibodies may be better targeting ligands.

bioRxiv · Mar 14, 2023Cancer Biology

Amyloidogenic Propensity of Self-Assembling Peptides and their Adjuvant Potential for use as DNA Vaccines

P. Shrimali, S. Chen, R. Dreher, M. Howard, J. Buck, D. Kim, J. Rudra, M. Jackrel

This study characterizes the amyloidogenic properties of a self-assembling peptide and demonstrates its safety and adjuvant potential as a DNA vaccine platform.

bioRxiv · Sep 9, 2022Bioengineering

External fertilization is orchestrated by a pH-regulated soluble adenylyl cyclase controlling sperm motility and chemotaxis

H. G. Koerschen, H. Hamzeh, R. Pascal, L. Alvarez, W. Boenigk, N. Kaur, L. Levin, J. Buck, C. Kambach, M. Michino, A. Jennings, A. Sato, R. Seifert, T. Struenker, C. Steegborn, U. B. Kaupp

This paper identifies a pH-regulated soluble adenylyl cyclase in non-mammalian sperm that controls motility and chemotaxis, revealing evolutionary adaptations to aquatic environments.

bioRxiv · Jun 18, 2021 · PreprintBiophysics

Soluble adenylyl cyclase inhibition prevents human sperm functions essential for fertilization

M. Balbach, L. Ghanem, T. Rossetti, N. Kaur, C. Ritagliati, J. Ferreira, D. Krapf, L. Puga, C. Santi, J. N. Hansen, D. Wachten, M. Fushimi, P. T. Meinke, J. Buck, L. R. Levin

This study shows that inhibiting soluble adenylyl cyclase (sAC) in human sperm prevents key functions needed for fertilization, suggesting sAC inhibitors as potential non-hormonal contraceptives.

bioRxiv · Apr 27, 2021Pharmacology & Toxicology

Non-canonical regulation of glycogenolysis and the Warburg phenotype by soluble adenylyl cyclase

J.-C. Chang, S. Go, E. H. Gilglioni, H. L. Li, H.-L. Huang, L. R. Levin, J. Buck, A. J. Verhoeven, R. P. J. Oude Elferink

This study shows that soluble adenylyl cyclase (sAC) regulates glycogenolysis and the Warburg phenotype by modulating cAMP signaling pathways.

bioRxiv · Feb 2, 2020 · PreprintBiochemistry