Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
4 papers
Recent·Most cited
S. Karki, M. Javanainen, D. Tranter…·V. Paavilainen
The paper determines the structure of the Sec61/TRAP complex bound to a ribosome using Cryo-EM, revealing how TRAP facilitates ER membrane remodeling and polypeptide translocation.
S. Rehan, D. Tranter, P. P. Sharp…·V. Paavilainen
This study describes KZR-8445, a cyclic depsipeptide that selectively inhibits Sec61-mediated protein biogenesis by mimicking signal peptides, showing efficacy in a rheumatoid arthritis model.
J. J. Kelly, D. Tranter, E. Pardon…·W. Yue
The paper captures structural snapshots of actin and tubulin folding within the TRiC chaperonin using cryo-EM, revealing how substrates interact with the chamber during folding.
E. Bertling, P. Blaesse, P. Seja…·E. Ruusuvuori
This study shows that CAVII regulates dendritic spine morphology and density by bundling actin filaments, distinct from CAII's role in pH buffering.