Author

A. Linke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. Frank· 1 shared A. Mueller· 1 shared A. Sivayoganathan· 1 shared B. Mair· 1 shared B. R. Daley· 1 shared C. F. Krebs· 1 shared C. L. Dalgard· 1 shared C. Meyer-Schwesinger· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. Frank

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2 papers

Recent·Most cited

SOS1 inhibition enhances the efficacy of and delays resistance to G12C inhibitors in lung adenocarcinoma

B. R. Daley, N. E. Sealover, E. Sheffels, J. M. Hughes, D. Gerlach, M. H. Hofmann, K. Kostyrko, B. Mair, A. Linke, Z. Beckley, A. Frank, C. L. Dalgard, R. L. Kortum

This study shows that SOS1 inhibition with BI-3406 enhances G12C inhibitor efficacy and delays resistance in lung adenocarcinoma by targeting resistance mechanisms and drug-tolerant persister cells.

bioRxiv · Dec 7, 2023 · PreprintCancer Biology

Transcriptional and clonal characterization of cytotoxic CD8+ T cells in crescentic glomerulonephritis

Y. Zhao, A. Mueller, H. Cicek, H.-J. Paust, A. Sivayoganathan, A. Linke, C. Wegscheid, T. Wiech, T. B. Huber, C. Meyer-Schwesinger, S. Bonn, U. P. Panzer, G. Tiegs, C. F. Krebs, K. Neumann

This study identifies clonally expanded cytotoxic CD8+ T cells in ANCA-associated cGN and shows their pathogenic role in kidney disease progression.

bioRxiv · Aug 31, 2022Immunology