M. Molina

Nucleocytoplasmic transport senses mechanics independently of cell density in cell monolayers.

The paper shows that nucleocytoplasmic transport (NCT) in cell monolayers responds to mechanical forces but not cell density, contrasting with YAP's response to both mechanics and cell density.

Using DNA flow-stretching assay as a tool to validate the tagging of DNA-binding proteins for single-molecule experiments

This paper uses a DNA flow-stretching assay to evaluate how a KCK tag affects DNA-binding protein behavior in single-molecule experiments.

Human Gasdermin D and MLKL disrupt mitochondria, endocytic traffic and TORC1 signaling in budding yeast

This study expresses human GSDMD and MLKL in yeast to investigate their effects on mitochondria, endocytic traffic, and TORC1 signaling, revealing their role in cell death and potential for drug discovery.

Metagenomic analysis of coprolites from three Late Pleistocene megaherbivores from the Southwestern United States.

This study analyzes metagenomic data from coprolites of three Late Pleistocene megaherbivores to assess how desiccation affects microbial community composition compared to modern samples.

Characterisation of tumour immune microenvironment remodelling following oncogene inhibition in preclinical studies using an optimised imaging mass cytometry workflow

The paper optimises an imaging mass cytometry workflow to study TME remodelling in mouse models after KRAS G12C inhibitor treatment.

The nucleus acts as a ruler tailoring cell responses to spatial constraints

The paper shows that the nucleus acts as a ruler by triggering contractile responses when confined, influencing cell migration and processes like cancer invasion and immune responses.

The TIR-domain containing effectors BtpA and BtpB from Brucella abortus block energy metabolism

This study shows BtpA and BtpB from Brucella abortus reduce host cell NAD+ levels by acting as NAD+ hydrolases, impairing energy metabolism and immune responses.

Klebsiella pneumoniae type VI secretion system-mediated microbial competition is PhoPQ controlled and reactive oxygen species dependent

This study identifies PhoPQ as a regulator of Klebsiella pneumoniae T6SS activity, which mediates microbial competition and is dependent on reactive oxygen species.