ImmunologybioRxiv
Nuclear envelope disruption triggers hallmarks of aging in lung alveolar macrophages
N. S. De Silva, G. P. F. Nader, F. Nadalin…·N. Manel
This study shows that Lamin A/C protects lung alveolar macrophages from nuclear envelope rupture and aging-related DNA damage, linking NE disruption to genomic instability and senescence.
DOI 10.1038/s43587-023-00488-w