Author

A. Odle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:virus· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1

Frequent Co-Authors

S. Perlman· 3 shared N. C. Wu· 2 shared R. Lei· 2 shared T. J. C. Tan· 2 shared A. Drelich· 1 shared A. Hage· 1 shared A. LeBeau· 1 shared A. N. Freiberg· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersMicrobiology

S. Perlman

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Author profile →

4 papers

Recent·Most cited

TRIM7 ubiquitinates SARS-CoV-2 membrane protein to limit apoptosis and viral replication

M. Gonzalez-Orozco, H.-c. Tseng, A. Hage, H. Xia, P. Behera, K. Afreen, Y. Penaflor-Tellez, M. I. Giraldo, M. Huante, L. Puebla-Clark, S. van Tol, A. Odle, M. Crown, N. Teruel, T. R. Shelite, , R. Rajsbaum

This study identifies TRIM7 as an E3-ubiquitin ligase that ubiquitinates SARS-CoV-2 M protein to inhibit apoptosis and viral replication.

bioRxiv · Jun 17, 2024Microbiology

Functional and antigenic characterization of SARS-CoV-2 spike fusion peptide by deep mutational scanning

R. Lei, E. Qing, A. Odle, M. Yuan, T. J. C. Tan, N. So, W. O. Ouyang, I. A. Wilson, T. Gallagher, S. Perlman, N. C. Wu, L. Y. R. Wong

This study uses deep mutational scanning to analyze the SARS-CoV-2 spike fusion peptide, identifying mutations affecting viral entry and antibody resistance.

bioRxiv · Nov 28, 2023Microbiology

Evidence of antigenic drift in the fusion machinery core of SARS-CoV-2 spike

T. J. C. Tan, A. Odle, R. Lei, K. A. Matreyek, S. Perlman, L.-Y. R. Wong, N. C. Wu

This study identifies S2 domain mutations in SARS-CoV-2 spike that reduce binding to antibodies, showing antigenic drift in this region and its impact on vaccine efficacy.

bioRxiv · Sep 27, 2023Microbiology

The Development of a Novel Nanobody Therapeutic for SARS-CoV-2

G. Ye, J. Gallant, C. Massey, K. Shi, W. Tai, J. Zheng, A. Odle, M. Vickers, J. Shang, Y. Wan, A. Drelich, K. Kempaiah, V. Tat, S. Perlman, L. Du, , F. Li

This paper develops a potent, low-cost nanobody therapeutic, Nanosota-1C-Fc, that effectively blocks SARS-CoV-2 infection in vitro and in vivo with high affinity and stability.

bioRxiv · Nov 17, 2020Microbiology