Broad ultra-potent neutralization of SARS-CoV-2 variants by monoclonal antibodies specific to the tip of RBD
H. Ma, Y. Guo, H. Tang, C.-T. Tseng, L. Wang, H. Zong, Z. Wang, Y. He, Y. Chang, S. Wang, H. Huang, Y. Ke, Y. Yuan, M. Wu, Y. Zhang, , J. Zhu
This paper identifies a monoclonal antibody, 2G1, that neutralizes all SARS-CoV-2 variants with high potency and describes its mechanism of action and therapeutic efficacy in animal models.
bioRxiv · Sep 24, 2021Cell Biology