Author

A. Pathni

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Upadhyaya· 2 shared A. P. Rapoport· 1 shared A. Wang· 1 shared D. Atanackovic· 1 shared D. Lum· 1 shared D. Yamoah· 1 shared E. Gebru· 1 shared E. Rosati· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBioengineering

A. Upadhyaya

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Preventing trogocytosis by cathepsin B inhibition augments CAR T cell function

K. A. Dietze, K. Nguyen, A. Pathni, F. Fazekas, W. Sun, E. Rosati, J. M. Baker, M. Galeana Figueroa, E. Gebru, D. Yamoah, R. Mulatu, A. Wang, A. P. Rapoport, D. Lum, X. Fan, , T. Luetkens

This study shows that inhibiting cathepsin B prevents CAR T cell fratricide and exhaustion by blocking trogocytosis, improving CAR T cell persistence and anti-tumor activity.

bioRxiv · Jun 11, 2024Bioengineering

A tug of war between filament treadmilling and myosin induced contractility generates actin rings

Q. Ni, K. Wagh, A. Pathni, H. Ni, V. Vashisht, A. Upadhyaya, G. Papoian

The paper uses simulations and experiments to show that actin ring formation in cells depends on the balance between filament treadmilling and myosin contractility.

bioRxiv · Jun 6, 2021Biophysics