Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
7 papers
Recent·Most cited
K. A. Dietze, K. Nguyen, A. Pathni, F. Fazekas, W. Sun, E. Rosati, J. M. Baker, M. Galeana Figueroa, E. Gebru, D. Yamoah, R. Mulatu, A. Wang, A. P. Rapoport, D. Lum, X. Fan, , T. Luetkens
This study shows that inhibiting cathepsin B prevents CAR T cell fratricide and exhaustion by blocking trogocytosis, improving CAR T cell persistence and anti-tumor activity.
bioRxiv · Jun 11, 2024Bioengineering
M. W. Pesesky, R. Bharanikumar, L. W. Le Bourhis, H. ElAbd, E. Rosati, C. Carty, N. Singh, B. Bokemeyer, S. Schreiber, S. Goerg, M. G. Noceda, P. Chapfuwa, R. M. Gittelman, D. H. May, J. N. Dines, , M. Allez
The paper identifies public TCRB sequences expanded in CD or UC, associated with HLA alleles and antigen-specific immune responses, showing differential expansion in CD compared to UC and healthy controls.
bioRxiv · May 15, 2024Immunology
E. A. Morales, K. A. Dietze, J. M. Baker, A. Wang, S. V. Avila, F. Iglesias, S. V. Radhakrishnan, E. Vander Mause, M. L. Olson, W. Sun, E. Rosati, S. L. Chidester, T. Iraguha, X. Fan, D. Atanackovic, T. Luetkens
The paper shows that modifying integrin-mediated adhesion in CAR T cells prevents CNS targeting while maintaining anti-tumor activity against Ewing sarcoma.
bioRxiv · Feb 8, 2024 · PreprintBioengineering
E. Rosati, M. V. Pogorelyy, A. A. Minervina, A. Franke, A. Scheffold, P. Bacher, P. Thomas
The paper identifies public CD4+ T cell clonotypes reactive to SARS-CoV-2 and predicts their HLA-restriction and epitopes using reverse epitope discovery.
bioRxiv · Nov 19, 2021Immunology
P. A. Mudd, A. A. Minervina, M. V. Pogorelyy, J. S. Turner, W. Kim, E. Kalaidina, J. Petersen, A. J. Schmitz, T. Lei, A. Haile, A. M. Kirk, R. C. Mettelman, J. C. Crawford, T. H. O. Nguyen, L. C. Rowntree, , A. Ellebedy
This study shows that SARS-CoV-2 mRNA vaccination leads to strong and long-lasting T follicular helper cell responses in humans.
bioRxiv · Sep 8, 2021Immunology
A. A. Minervina, E. A. Komech, A. Titov, M. Bensouda Koraichi, E. Rosati, I. Z. Mamedov, A. Franke, G. A. Efimov, D. M. Chudakov, T. Mora, A. M. Walczak, Y. B. Lebedev, M. V. Pogorelyy
This study tracks T cell memory formation after mild COVID-19 infection using longitudinal TCR sequencing, showing clonal expansion and memory phenotype acquisition in infected individuals.
bioRxiv · May 18, 2020Immunology
A. A. Minervina, M. V. Pogorelyy, E. A. Komech, V. K. Karnauhov, P. Bacher, E. Rosati, A. Franke, D. M. Chudakov, I. Z. Mamedov, Y. B. Lebedev, T. Mora, A. M. Walczak
The paper tracks T-cell clone dynamics and TCR repertoire changes after primary and secondary yellow fever vaccination using single-cell RNAseq and TCRseq.
bioRxiv · Oct 25, 2019 · PreprintImmunology