Author

C. Herman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 4 Research Focus:gene regulatory network inference· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2

Frequent Co-Authors

J. P. Pribis· 3 shared P. J. Hastings· 3 shared S. M. Rosenberg· 3 shared Y. Zhai· 3 shared C. Coarfa· 2 shared D. Bates· 2 shared D. M. Fitzgerald· 2 shared J. Xia· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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3 shared papersMicrobiology

J. P. Pribis

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Author profile →

7 papers

Recent·Most cited

Dietary protein shapes the profile and repertoire of intestinal CD4+ T cells

A. Lockhart, A. Reed, T. B. R. de Castro, C. Herman, M. C. C. Canesso, D. Mucida

This study shows dietary proteins influence intestinal CD4+ T cell profiles and receptor repertoires, affecting their transcriptional programs and responses to food antigens.

bioRxiv · Apr 11, 2023 · PreprintImmunology

Telomere dysfunction impairs intestinal differentiation andpredisposes to diet-induced colitis

M. Engevik, L. Guo, W.-S. Song, C. Chronowski, V. Akhanov, N. Bosquez, A. Engevik, N. Oezguen, C. Coarfa, N. Putluri, A. Catic, J. Baur, M. Finegold, N. Shroyer, J. Gu, , E. Sahin

This study shows that telomere shortening impairs intestinal differentiation, leading to barrier defects and diet-induced colitis through microbiome modulation and nutrient flux.

bioRxiv · Jul 14, 2022 · PreprintCell Biology

ppGpp and RNA-Polymerase Backtracking Guide Antibiotic-Induced Mutable Gambler Cells

Y. Zhai, P. J. Minnick, J. P. Pribis, L. Garcia-Villada, P. J. Hastings, C. Herman, S. M. Rosenberg

The paper identifies the stringent starvation response as a key driver of ciprofloxacin-induced mutagenesis through RNA polymerase and ppGpp-mediated DNA-damage signaling.

bioRxiv · Jul 6, 2022Microbiology

Biology and engineering of integrative and conjugative elements: Construction and analyses of hybrid ICEs reveal element functions that affect species-specific efficiencies

E. L. Bean, C. Herman, A. D. Grossman

The paper constructs hybrid integrative and conjugative elements (ICEs) by combining modules from Tn916 and ICEBs1 to study their transfer efficiencies into different bacterial species.

bioRxiv · Dec 16, 2021Microbiology

HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics

A. R. Strom, R. J. Biggs, E. J. Banigan, X. Wang, K. Chiu, C. Herman, J. Collado, F. Yue, J. C. Ritland Politz, L. J. Tait, D. Scalzo, A. Telling, M. Groudine, C. P. Brangwynne, J. Marko, A. D. Stephens

This study shows HP1α crosslinks chromatin to maintain nuclear and mitotic chromosome mechanics, independent of histone methylation.

bioRxiv · Oct 9, 2020Biophysics

Gamblers: an Antibiotic-induced Evolvable Cell Subpopulation Differentiated by Reactive-oxygen-induced General Stress Response

J. P. Pribis, L. Garcia-Villada, Y. Zhai, O. Lewin-Epstein, A. Wang, J. Liu, J. Xia, Q. Mei, D. M. Fitzgerald, J. Bos, R. Austin, C. Herman, D. Bates, L. Hadany, P. J. Hastings, S. M. Rosenberg

The paper shows ciprofloxacin induces antibiotic-resistant mutations by creating a subpopulation of cells with activated sigma-S response, which allows error-prone repair and generates cross-resistant mutants.

bioRxiv · Dec 11, 2018Microbiology

Bacteria-to-human protein networks reveal origins of endogenous DNA damage

J. Xia, L.-Y. Chiu, R. B. Nehring, M. A. Bravo Nunez, Q. Mei, M. Perez, Y. Zhai, D. M. Fitzgerald, J. P. Pribis, Y. Wang, C. W. Hu, R. T. Powell, S. A. LaBonte, A. Jalali, M. L. Matadamas Guzman, , S. M. Rosenberg

The paper identifies DNA-damaging proteins in E. coli and their human homologs, showing they promote endogenous DNA damage and are overrepresented in cancer drivers.

bioRxiv · Jun 26, 2018Cancer Biology