PhysiologybioRxiv
Age-dependent RGS5 loss in pericytes induces cardiac dysfunction and fibrosis in the heart
A. Tamiato, L. S. Tombor, A. Fischer…·G. Luxan
This study shows that loss of RGS5 in pericytes with age leads to cardiac dysfunction and fibrosis by altering pericyte function and activating fibroblasts.