D. White

Mathematical model for rod outer segment dynamics during retinal detachment and reattachment

This study develops a mathematical model to analyze how retinal detachment affects rod outer segment renewal and identifies disc removal rate as critical for recovery.

Overexpression of Rheb, a positive Tor regulator, reveals principles of rod outer segment size control

This study shows that increasing rod outer segment growth in zebrafish does not lead to accelerated shedding, revealing principles of size control.

Nanotrap Particles Improve Nanopore Sequencing of SARS-CoV-2 and Other Respiratory Viruses

The paper introduces a magnetic hydrogel particle method to improve nanopore sequencing of SARS-CoV-2 and other respiratory viruses from diagnostic samples.

Cohesion in male singing behavior predicts group reproductive output in a social songbird

The paper shows that cohesive male singing behavior in brown-headed cowbirds predicts group reproductive success, with experimental manipulation reducing cohesion and reproductive output.

Shifting sensitivity and signal-dependent timing in the copulatory displays of songbirds

The paper quantifies female brown-headed cowbird copulation solicitation displays using computer vision, showing that song potency and female responsivity predict display duration and latency.

Oxylipin metabolism is controlled by mitochondrial b-oxidation during bacterial inflammation.

This study shows that mitochondrial β-oxidation removes oxylipins during bacterial inflammation, with CPT1 playing a key role, and identifies associated genetic upregulation in human sepsis.

A rapidly adaptable biomaterial vaccine for SARS-CoV-2

This study develops a biomaterial vaccine using mesoporous silica rods to deliver SARS-CoV-2 antigens and adjuvants, showing rapid antibody responses and neutralizing activity.

Ferrochelatase regulates retinal neovascularization

This paper shows that inhibiting ferrochelatase (FECH) reduces retinal neovascularization and promotes physiological angiogenesis in a mouse model, suggesting FECH inhibitors could treat retinal diseases.

Metabolic dysregulation of the lysophospholipid/autotaxin axis in the chromosome 9p21 gene SNP rs10757274

The paper identifies metabolic dysregulation of lysophospholipid/autotaxin pathways linked to a CHD risk SNP, showing altered lipid metabolism and enzyme expression in multiple models.

High-Throughput Single-Molecule Analysis via Divisive Segmentation and Clustering

The paper introduces DISC, a platform that accelerates single-molecule trajectory analysis with divisive clustering, revealing a lack of cooperativity in HCN channel domains.

Microbial biogeography of 1,000 geothermal springs in New Zealand

This study analyzes microbial communities in 1,019 geothermal springs across New Zealand to identify factors influencing biogeographical patterns, finding pH as the primary driver of diversity and two dominant genera shaping community composition.