Author

B. Hinz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1

Frequent Co-Authors

A. J. Fisher· 1 shared A. Kapus· 1 shared A. Nazgiewicz· 1 shared A. S. Loudon· 1 shared D. A. Bechtold· 1 shared D. W. Ray· 1 shared E. Cortes· 1 shared G. B. Kitchen· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperCell Biology

A. J. Fisher

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Myocardin-related transcription factor drives epithelial fibrogenesis in polycystic kidney disease

Z. Lichner, M. Ding, T. Khare, Q. Dan, R. Benitez, M. Praszner, X. Song, R. Saleeb, B. Hinz, Y. Pei, K. Szaszi, A. Kapus

This study identifies MRTF as a key mediator of fibrosis in PKD by showing its activation following PC1/2 loss and its role in epithelial fibrogenesis.

bioRxiv · Mar 15, 2024 · PreprintCell Biology

FLECS Technology for High-Throughput Screening of Hypercontractile Cellular Phenotypes in Fibrosis: A Function-First Approach to Anti-Fibrotic Drug Discovery

Y. Wang, E. Cortes, R. Huang, J. Wan, B. Hinz, R. Damoiseaux, I. Pushkarsky

This study develops a high-throughput screening platform to identify anti-fibrotic compounds by quantifying myofibroblast contractility in response to TGF-β1.

bioRxiv · Jul 21, 2023Bioengineering

Modeling Mechanical Activation of Macrophages During Pulmonary Fibrogenesis for Targeted Anti-Fibrosis Therapy

Y. Xu, L. Ying, J. K. Lang, B. Hinz, R. Zhao

This study models mechanical activation of macrophages in fibrotic lung tissue and shows pirfenidone inhibits this activation, offering a new mechanism for anti-fibrosis therapy.

bioRxiv · Jul 19, 2023Bioengineering

The circadian clock protein REVERBα inhibits pulmonary fibrosis development

P. S. Cunningham, P. Meijer, A. Nazgiewicz, S. G. Anderson, L. A. Borthwick, J. Bagnall, G. B. Kitchen, M. Lodyga, N. Begley, R. V. Venkateswaran, R. Shah, P. F. Mercer, H. J. Durrington, N. C. Henderson, K. Piper-Hanley, , J. Blaikley

This study identifies REVERBα as a regulator of pulmonary fibrosis by modulating circadian rhythms and integrin β1 focal adhesion formation in fibroblasts, with potential therapeutic implications.

bioRxiv · Sep 25, 2019Cell Biology