Author

B. J. Polacco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:cryo-EM· 1 Organism:human· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

N. J. Krogan· 3 shared A. Garcia-Sastre· 2 shared D. L. Swaney· 2 shared L. Zuliani-Alvarez· 2 shared M. Soucheray· 2 shared A. Cupic· 1 shared A. L. Richards· 1 shared A. Marin· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersMicrobiology

N. J. Krogan

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologybioRxivOct 18, 2022

Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis.

T. Kehrer, A. Cupic, C. Ye…·L. Miorin

This study shows SARS-CoV-2 ORF6 disrupts nucleo-cytoplasmic trafficking, inhibits IFN signaling, and modulates viral protein expression, with variant polymorphisms affecting its function.

DOI 10.1016/j.chom.2023.08.003

mouseproteomics

𝕏 PostBluesky

BiophysicsbioRxivSep 28, 2022

De novo protein identification in mammalian sperm using high-resolution in situ cryo-electron tomography

Z. Chen, M. Shiozaki, K. M. Haas…·D. A. Agard

The paper identifies novel sperm proteins in mammals using cryo-electron tomography and AlphaFold2 models, revealing their structural roles in flagellar mechanics.

DOI 10.1016/j.cell.2023.09.017

mousecryo-EM

𝕏 PostBluesky

MicrobiologybioRxivPreprintJun 6, 2021

Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant

L. G. Thorne, M. Bouhaddou, A.-K. Reuschl…·N. J. Krogan

This study identifies that the B.1.1.7 SARS-CoV-2 variant enhances innate immune evasion through increased Orf9b and Orf6 expression and activity.

DOI 10.1101/2021.06.06.446826

humanproteomics

𝕏 PostBluesky