Author

B. Paul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Biophysics· 2 Biochemistry· 1 Microbiology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 3 Organism:human· 3 Assay:proteomics· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Organism:Drosophila· 2

Frequent Co-Authors

W. M. Henne· 4 shared G. Montoya· 2 shared H. Merta· 2 shared R. Ugrankar-Banerjee· 2 shared S. Tran· 2 shared A. Kovalenko· 1 shared A. L. Ankrum· 1 shared B. Collins· 1 shared

Activity by Year

2020-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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4 shared papersCell Biology

W. M. Henne

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Paraoxonase-like APMAP maintains endoplasmic reticulum-associated lipid and lipoprotein homeostasis

B. Paul, H. Merta, R. Ugrankar-Banerjee, M. Hensley, S. Tran, G. Dias do Vale, J. G. McDonald, S. A. Farber, W. M. Henne

This paper identifies APMAP as an ER-localized antioxidant that maintains lipid and lipoprotein homeostasis, with loss of APMAP causing ER stress, lipid droplet accumulation, and altered lipoprotein maturation across multiple organisms.

bioRxiv · Jan 26, 2024Cell Biology

Spatial proteomics of ER tubules reveals CLMN, an ER-actin tether at focal adhesions that promotes cell migration

H. Merta, T. Isogai, B. Paul, G. Danuser, W. M. Henne

The paper maps the human ER subdomain proteome, identifies CLMN as an ER-actin tether at focal adhesions, and shows it promotes cell migration by regulating actin dynamics and calcium signaling.

bioRxiv · Jan 24, 2024Cell Biology

In-depth characterisation of a selection of gut commensal bacteria reveals their functional capacities to metabolise dietary carbohydrates with prebiotic potential

B.-F. Cassandre, B. Paul, P. Frederic, V. Sarah, C. Cyril, C. Florence, C. Celine, R. Olivier, H.-A. Christelle, L. Philippe, C. Cherbuy

This study examines the metabolic capacities of gut commensal bacteria toward prebiotic carbohydrates, revealing strain-specific effects on metabolite production and gene expression.

bioRxiv · Jan 16, 2024 · PreprintMicrobiology

Reduced male fertility of an Antarctic mite following extreme heat stress could prompt localized population declines

J. B. Benoit, G. Finch, A. L. Ankrum, J. Niemantsverdriet, B. Paul, M. Kelley, J. D. Gantz, R. E. Lee, D. L. Denlinger

This study shows that extreme heat stress reduces male fertility in Antarctic mites, potentially leading to population declines.

bioRxiv · Apr 11, 2023Physiology

The fat body cortical actin network regulates Drosophila inter-organ nutrient trafficking, signaling, and adipose cell size

R. Ugrankar-Banerjee, S. Tran, J. Bowerman, A. Kovalenko, B. Paul, W. M. Henne

This study shows that Act5C-dependent cortical actin networks in Drosophila fat body regulate adipose cell size, lipid trafficking, and signaling during development.

bioRxiv · Jun 15, 2022Cell Biology

Structural predictions of the SNX-RGS proteins suggest they belong to a new class of lipid transfer proteins

B. Paul, S. Weeratunga, V. A. Tillu, H. Hariri, W. M. Henne, B. Collins

The paper uses AlphaFold2 to predict the structure of SNX-RGS proteins, revealing a new class of lipid transfer proteins with a conserved hydrophobic pocket.

bioRxiv · Nov 30, 2021Biochemistry

Cas12a is a dynamic and precise RNA-guided nuclease without off-target activity on {lambda}-DNA

B. Paul, L. Chaubet, E. Verver, G. Montoya

This study investigates Cas12a's DNA binding and cleavage mechanisms using optical tweezers and fluorescence, showing it cleaves only the target site without off-target activity on λ-DNA.

bioRxiv · Jun 9, 2021 · PreprintBiophysics

DeepFRET: Rapid and automated single molecule FRET data classification using deep learning

J. Thomsen, M. B. Sletfjerding, S. Stella, B. Paul, S. B. Jensen, M. G. Malle, T. Petersen, G. Montoya, N. S. Hatzakis

DeepFRET automates smFRET data classification using deep learning, achieving >95% accuracy and speed compared to human operators.

bioRxiv · Jun 26, 2020Biophysics