W. M. Henne

The paper identifies Tld1 as a regulator of triglyceride lipolysis that specifically targets TG-rich lipid droplets and modulates lipolysis in yeast.

This study shows that Act5C-dependent cortical actin networks in Drosophila fat body regulate adipose cell size, lipid trafficking, and signaling during development.

The paper shows glucose restriction induces liquid-crystalline phase transitions in lipid droplets by promoting TG lipolysis, which alters lipid composition and remodels the proteome.

The paper uses AlphaFold2 to predict the structure of SNX-RGS proteins, revealing a new class of lipid transfer proteins with a conserved hydrophobic pocket.

The paper identifies ER-localized phosphatidylethanolamine synthase (Psd1) as a novel regulator of lipid droplet formation, showing its conserved role across species.

The paper shows glucose restriction induces liquid-crystalline lipid phase transitions in lipid droplets, which selectively remodel the LD proteome and affect ER-LD transport.

The paper develops a method to release lipids from the vacuole in yeast to study lipid metabolism and transport, showing Mdm1 facilitates sphingoid base to ceramide conversion and cholesterol can restore cell proliferation under sterol deprivation.