MicrobiologybioRxiv
Theoretical Considerations and Empirical Predictions of the Pharmaco- and Population Dynamics of Heteroresistance
B. R. R. Levin, B. A. Berryhill, T. Gil-Gil…·F. Baquero
This paper develops two mathematical models of heteroresistance to explore how resistance ascends and reverts during antibiotic treatment, showing that current identification methods are insufficient.
DOI 10.1073/pnas.2318600121