Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
T. R. Lane, J. Fu, B. Sherry…·S. Ekins
This study develops a potent EV-D68 inhibitor, 11526092, showing improved in vitro potency and in vivo efficacy compared to pleconaril, with strain-dependent structural effects observed via cryo-EM.
M. D. Sacco, C. Ma, P. Lagarias…·J. Wang
This study determines the structure of SARS-CoV-2 Mpro with calpain inhibitors and analogues, revealing new insights for developing dual inhibitors against Mpro and cathepsin L.
Y. Hu, C. Ma, T. Szeto…·J. Wang
This study identifies four compounds with broad-spectrum antiviral activity against multiple coronaviruses, including SARS-CoV-2, by inhibiting viral Mpro and cathepsin L.
M. Westberg, Y. Su, X. Zou…·M. Lin
The paper designs a new class of protease inhibitors targeting coronavirus Mpro, identifying ML1000 as a potent inhibitor with low-nanomolar affinity and antiviral activity.
C. Ma, M. D. Sacco, B. Hurst…·J. Wang
This study identifies inhibitors of SARS-CoV-2 main protease that show potent antiviral activity in cell culture.