Author

C. A. Haselwandter

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:cryo-EM· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

R. MacKinnon· 3 shared Y. Guo· 2 shared Z. Fu· 2 shared A. J. North· 1 shared G. Vaisey· 1 shared P. Banerjee· 1 shared

Activity by Year

2022-2022 · peak 3/yr

Co-Author Collaboration Network

6 top collaborators · 9 mutual co-author links

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3 shared papersBiophysics

R. MacKinnon

Mutual co-authors in cluster

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3 papers

Recent·Most cited

BiochemistrybioRxivAug 10, 2022

Piezo1 as a force-through-membrane sensor in red blood cells.

G. Vaisey, P. Banerjee, A. J. North…·R. MacKinnon

This study investigates Piezo1 distribution and dynamics in red blood cells, finding it preferentially localizes to the dimple and exhibits curvature coupling behavior.

DOI 10.7554/elife.82621

humanimaging

𝕏 PostBluesky

BiophysicsbioRxivJul 1, 2022

Elastic properties and shape of the Piezo dome underlying its mechanosensory function

C. A. Haselwandter, Y. Guo, Z. Fu, R. MacKinnon

The paper determines the force-distortion relationship of Piezo channels using vesicle shape measurements and derives their intrinsic curvature and bending stiffness.

DOI 10.1073/pnas.2208034119

statistical model

𝕏 PostBluesky

BiophysicsbioRxivJun 28, 2022

Quantitative prediction and measurement of Piezo's membrane footprint

C. A. Haselwandter, Y. Guo, Z. Fu, R. MacKinnon

The paper predicts and measures the membrane footprint of Piezo proteins using elasticity theory and cryo-electron tomography, showing agreement across vesicle sizes and revealing a spherical cap geometry.

DOI 10.1073/pnas.2208027119

cryo-EMstatistical model

𝕏 PostBluesky