Author

C. A. Lyssiotis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 23 Immunology· 5 Biochemistry· 2 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 28 Organism:human· 21 Organism:mouse· 16 Research Focus:cancer & tumor microenvironment· 15 Assay:bulk RNA-seq· 14 Assay:metabolomics· 14 Assay:proteomics· 11 Research Focus:metabolism & bioenergetics· 9

Frequent Co-Authors

L. Zhang· 17 shared P. Sajjakulnukit· 11 shared C. J. Halbrook· 10 shared M. Pasca di Magliano· 9 shared A. Andren· 8 shared Y. M. Shah· 8 shared H.-J. Lee· 7 shared S. A. Kerk· 6 shared

Activity by Year

2018-2024 · peak 10/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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17 shared papersCancer Biology

L. Zhang

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Author profile →

32 papers

Recent·Most cited

Cancer BiologybioRxivPreprintOct 30, 2019

Hypoxia inducible factor-2α increases sensitivity of colon cancer cells towards oxidative cell death

R. Singhal, K. P. Olive, C. A. Lyssiotis, Y. M. Shah

This study shows that HIF-2α overexpression makes colon cancer cells more sensitive to oxidative cell death, suggesting a potential therapeutic strategy.

DOI 10.1101/823997

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivNov 5, 2018

Macrophage Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer

C. J. Halbrook, C. Pontious, H.-J. Lee…·C. A. Lyssiotis

This study shows macrophages in pancreatic cancer release pyrimidines that inhibit gemcitabine therapy by competing with the drug for uptake and metabolism, and reducing macrophage burden improves treatment response.

DOI 10.1016/j.cmet.2019.02.001

mousehuman

𝕏 PostBluesky