Author

C. Bowen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Assay:clinical cohort / trial· 1 Research Focus:genome assembly· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:variant calling· 1

Frequent Co-Authors

A. Alazami· 1 shared A. B. Johnston· 1 shared C. P. Mata· 1 shared C. Rooryck· 1 shared D. MacDonald· 1 shared F. Gothe· 1 shared F. Pelluard· 1 shared H. Almousa· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperImmunology

A. Alazami

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2 papers

Recent·Most cited

Methylome-dependent transformation of emm1 group A streptococci

J. Alves, J. D. Rand, A. B. Johnston, C. Bowen, N. N. Lynskey

This paper identifies a methylome-dependent restriction barrier in emm1 group A streptococci that limits transformation and presents an improved protocol using phage anti-restriction protein Ocr to overcome this barrier.

bioRxiv · Apr 10, 2023 · PreprintMicrobiology

Human IL-2 receptor β mutations associated with defects in immunity and peripheral tolerance

Z. Zhang, F. Gothe, P. Pennamen, J. James, D. MacDonald, C. P. Mata, Y. Modis, M. Acres, W. Haller, C. Bowen, R. Doffinger, J. Sinclair, S. Brothers, A. Alazami, Y. Zhang, , M. J. Lenardo

This study identifies IL-2Rβ gene mutations causing immune and tolerance defects, showing variable expression impacts on T and NK cells and informing IL-2-based therapies.

bioRxiv · Nov 26, 2018Immunology