Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
6 papers
Recent·Most cited
A. Priddey, M. X. H. Chen-Xu, D. J. Cooper, S. MacMillan, G. Meisl, C. K. Xu, M. Hosmillo, I. G. Goodfellow, R. Kollyfas, R. Doffinger, J. R. Bradley, I. I. Mohorianu, R. Jones, T. P. J. Knowles, R. Smith, V. Kosmoliaptsis
bioRxiv · Oct 22, 2023Immunology
B. Meng, I. Ferreira, A. Abdullahi, N. Goonawardane, A. Saito, I. Kimura, D. Yamasoba, S. A. Kemp, G. Papa, S. Fatihi, S. Rathore, P. Perera Gerba, T. Ikeda, M. Toyoda, T. S. Tan, , S. Zepeda
This study investigates the immune escape, infectivity, and cell-cell fusion properties of SARS-CoV-2 Omicron BA.1 compared to Delta, showing higher ACE2 affinity and antibody evasion but similar antiviral drug efficacy.
bioRxiv · Dec 17, 2021Microbiology
P. Pereyra Gerber, L. M. Duncan, E. J. Greenwood, S. Marelli, A. Naamati, A. Teixeira-Silva, T. W. Crozier, I. Gabaev, J. R. Zhan, T. E. Mulroney, E. C. Horner, R. Doffinger, A. E. Willis, J. E. Thanventhiran, A. V. Protasio, N. J. Matheson
This paper develops a luminescent biosensor and reporter cell line to quantify SARS-CoV-2 infection and neutralising antibodies efficiently.
bioRxiv · Mar 22, 2021Microbiology
G. W. Carnell, K. A. Ciazynska, D. A. Wells, X. Xiong, E. T. Aguinam, S. H. McLaughlin, D. Mallery, S. Ebrahimi, L. Ceron-Gutierrez, L. C. James, R. Doffinger, J. L. Heeney, J. A. G. Briggs
This study evaluates closed-state SARS-CoV-2 spike protein immunization in mice, finding it induces potent neutralizing antibodies and T-cell responses, with unique binding properties compared to standard S protein constructs.
bioRxiv · Jan 14, 2021Immunology
X. Xiong, K. Qu, K. A. Ciazynska, M. Hosmillo, A. P. Carter, S. Ebrahimi, Z. Ke, S. H. W. Scheres, L. Bergamaschi, G. L. Grice, Y. Zhang, The CITIID-NIHR COVID-19 BioResource Collaboration, J. A. Nathan, S. Baker, L. C. James, , J. A. G. Briggs
This paper designs a thermostable, closed SARS-CoV-2 spike protein trimer that remains in the pre-fusion state and can be used in serological assays.
bioRxiv · Jun 15, 2020Biochemistry
Z. Zhang, F. Gothe, P. Pennamen, J. James, D. MacDonald, C. P. Mata, Y. Modis, M. Acres, W. Haller, C. Bowen, R. Doffinger, J. Sinclair, S. Brothers, A. Alazami, Y. Zhang, , M. J. Lenardo
This study identifies IL-2Rβ gene mutations causing immune and tolerance defects, showing variable expression impacts on T and NK cells and informing IL-2-based therapies.
bioRxiv · Nov 26, 2018Immunology