Author

C. Gain

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 3 Cancer Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Approach:experimental assay· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

O. Francois· 3 shared A. Saha· 2 shared S. Malik· 2 shared A. Ghosh· 1 shared B. B. Das· 1 shared B. Bhattacharya· 1 shared B. Rhone· 1 shared D. Ghosh· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersEvolutionary Biology

O. Francois

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Author profile →

5 papers

Recent·Most cited

Differential Carbonic Anhydrase Activities Control EBV-Induced B-Cell Transformation and Lytic Cycle Reactivation

S. Malik, J. Biswas, P. Sarkar, S. Nag, C. Gain, S. Ghosh Roy, B. Bhattacharya, D. Ghosh, A. Saha

This study shows that differential carbonic anhydrase activities regulate EBV-induced B-cell transformation and lytic cycle reactivation through transcriptional control by EBNA2 and BZLF1.

bioRxiv · Sep 8, 2023Microbiology

A quantitative theory for genomic offset statistics

C. Gain, B. Rhone, P. CUBRY, I. Salazar, F. Forbes, y. Vigouroux, F. Jay, O. Francois

The paper develops a theoretical framework to interpret genomic offset statistics and validates it using simulations and empirical data on African pearl millet.

Molecular Biology and Evolution · Jun 12, 2023Peer-reviewedEvolutionary Biology

A Spectral Theory for Wright's Inbreeding Coefficients and Related Quantities

O. Francois, C. Gain

This paper establishes a theoretical link between Wright's inbreeding coefficient and PCA, showing they provide equivalent descriptions of population structure.

bioRxiv · Oct 7, 2020Evolutionary Biology

LEA 3: Factor models in population genetics and ecological genomics with R

C. Gain, O. Francois

The paper introduces new functionalities in the LEA R package for ecological genomics, including genotype imputation, latent factor models, and climate-based genetic offset estimation.

bioRxiv · Oct 6, 2020Evolutionary Biology

Proteasomal Inhibition Triggers Viral Oncoprotein Degradation via Autophagy-Lysosomal Pathway

C. Gain, S. Malik, S. Bhattacharjee, A. Ghosh, E. S. Robertson, B. B. Das, A. Saha

This study shows proteasomal inhibition causes degradation of EBNA3A and EBNA3C viral oncoproteins via autophagy-lysosomal pathway, while EBNA3B remains stable, suggesting potential therapeutic use of proteasome inhibitors for EBV-related B-cell lymphomas.

bioRxiv · Sep 23, 2019Cancer Biology