Author

S. Nag

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1 Cell Biology· 1 Ecology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

W. Ma· 3 shared A. S. Bhat· 2 shared H. Gong· 2 shared L. Qi· 2 shared S. Gollapudi· 2 shared T. Irving· 2 shared A. C. Combs· 1 shared A. Chakraborty· 1 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersPhysiology

W. Ma

Mutual co-authors in cluster

Author profile →

10 papers

Recent·Most cited

Cooperation Destabilizes Communities, but Competition Pays the Price

A. S. Bhat, S. Nag, S. Dey

The paper studies how external perturbations affect ecological communities, finding that cooperative interactions increase extinction risk but leave some species intact, leading to a community with more cooperation.

bioRxiv · Dec 26, 2023Ecology

Differential Carbonic Anhydrase Activities Control EBV-Induced B-Cell Transformation and Lytic Cycle Reactivation

S. Malik, J. Biswas, P. Sarkar, S. Nag, C. Gain, S. Ghosh Roy, B. Bhattacharya, D. Ghosh, A. Saha

This study shows that differential carbonic anhydrase activities regulate EBV-induced B-cell transformation and lytic cycle reactivation through transcriptional control by EBNA2 and BZLF1.

bioRxiv · Sep 8, 2023Microbiology

Myosin in autoinhibited off state(s), stabilized by mavacamten, can be recruited via inotropic effectors

W. Ma, C. L. del Rio, L. Qi, M. Prodanovic, S. Mijailovich, C. Zambataro, H. Gong, R. Shimkunas, S. Gollapudi, S. Nag, T. Irving

This paper shows that mavacamten stabilizes myosin in off states, which can still be recruited by physiological inotropic effectors to maintain cardiac function.

bioRxiv · Apr 10, 2023 · PreprintPhysiology

A small-molecule myosin inhibitor as a targeted multi-stage antimalarial

D. V. Trivedi, A. Karabina, G. Bergnes, A. Racca, H. Wander, S. Jung, N. Mittal, T. Huijs, S. Ouchida, P. V. Ruijgrok, D. Song, S. Wittlin, P. Mukherjee, A. Chakraborty, E. A. Winzeler, , J. Spudich

This paper develops a small-molecule myosin inhibitor, KNX-115, effective against multiple stages of Plasmodium infection with high selectivity and potency.

bioRxiv · Sep 9, 2022 · PreprintPharmacology & Toxicology

ATG9 vesicles comprise the seed membrane of mammalian autophagosomes

T. J. Olivas, Y. Wu, S. Yu, L. Luan, P. Choi, S. Nag, P. De Camilli, K. Gupta, T. J. Melia

This study identifies ATG9 vesicles as the seed membrane for mammalian autophagosomes, showing they integrate proteins like LC3-II and are diluted as autophagosomes expand.

bioRxiv · Aug 16, 2022 · PreprintCell Biology

Assessment of local potato cultivars found in Cis-Himalayan region of West Bengal through morphology and biochemical profiling

S. Dutta, S. Chakraborty, B. J. Reddy, S. Nag, S. Nath, S. Routh, V. Behera, G. J. Lazar, B. Monika, L. Hijam, M. Chakraborty, S. K. Roy, A. Choudhury, S. Hembram, M. K. Debnath, R. Mandal

This study evaluates local potato cultivars from North Bengal for morphology and anthocyanin content to identify stable genotypes with high tuber yield and antioxidant properties.

bioRxiv · Apr 27, 2022 · PreprintPlant Biology

Cardiac myosin filaments are directly regulated by calcium

W. Ma, H. Gong, L. Qi, S. Nag, T. Irving

This study shows that cardiac myosin filaments are directly regulated by calcium, transitioning from inactive to active states through structural changes.

bioRxiv · Feb 19, 2022Biophysics

TWO CLASSES OF MYOSIN INHIBITORS, BLEBBISTATIN AND MAVACAMTEN, STABILIZE β-CARDIAC MYOSIN IN DIFFERENT STRUCTURAL AND FUNCTIONAL STATES

S. K. Gollapudi, W. Ma, S. Chakravarthy, A. C. Combs, N. Sa, S. Langers, T. C. Irving, S. Nag

This study compares how two myosin inhibitors, mavacamten and blebbistatin, stabilize myosin in distinct structural and functional states, potentially affecting cardiac function differently.

bioRxiv · Dec 19, 2020 · PreprintBiochemistry

A colony-level optimization model provides a potential mechanism for the evolution of novel castes in eusocial ant colonies

S. Nag, A. S. Bhat

The paper develops an economics-based optimization model to explain the evolution of novel castes in ant colonies, showing it aligns with empirical observations.

bioRxiv · Oct 8, 2020Evolutionary Biology

CONSERVED INTERACTIONS IN CARDIAC SYNTHETIC THICK FILAMENTS DIFFERENTLY AFFECT MYOSIN SUPER-RELAXED STATE IN HEALTHY, DISEASE AND MAVACAMTEN-TREATED MODELS

S. Gollapudi, S. Nag

bioRxiv · Aug 6, 2020Biochemistry