C. GeurtsvanKessel

This study inoculates Syrian golden hamsters with SARS-CoV-2 Omicron BA.1 to compare its pathogenicity and viral shedding to Delta, finding reduced clinical signs and viral shedding but still pneumonia, with pre-existing immunity offering protection.

This study compares the antigenic differences between SARS-CoV-2 Omicron BA.1 and BA.2 variants using antigenic cartography and hamster sera, finding they are distinct antigenic outliers.

This study examines the temporal changes in viral RNA and cytokine levels in hospitalized COVID-19 patients, finding differences in RNAemia duration and cytokine associations with disease severity.

This study shows that high-dose convalescent plasma or monoclonal antibodies protect hamsters from SARS-CoV-2-induced lower respiratory disease, but lower doses are ineffective.