Author

D. Noack

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

B. Rockx· 4 shared B. L. Haagmans· 3 shared M. M. Lamers· 3 shared R. D. de Vries· 3 shared B. Haagmans· 2 shared C. GeurtsvanKessel· 2 shared D. van Riel· 2 shared K. S. Schmitz· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersMicrobiology

B. Rockx

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The pro-inflammatory response to influenza A virus infection is fueled by endothelial cells

L. Bauer, L. Rijsbergen, L. Leijten, F. F. W. Benavides, D. Noack, M. M. Lamers, B. L. Haagmans, R. D. de Vries, R. L. de Swart, D. van Riel

This study shows that endothelial cells are abortively infected by influenza A virus and contribute to systemic inflammation through increased cytokine secretion in co-cultures with infected epithelial cells.

bioRxiv · Aug 19, 2022Microbiology

Pulmonary lesions following inoculation with the SARS-CoV-2 Omicron BA.1 (B.1.1.529) variant in Syrian golden hamsters

M. Rissmann, D. Noack, D. van Riel, K. S. Schmitz, R. D. de Vries, P. van Run, M. M. Lamers, C. GeurtsvanKessel, M. Koopmans, R. Fouchier, T. Kuiken, B. Haagmans, B. Rockx

This study inoculates Syrian golden hamsters with SARS-CoV-2 Omicron BA.1 to compare its pathogenicity and viral shedding to Delta, finding reduced clinical signs and viral shedding but still pneumonia, with pre-existing immunity offering protection.

bioRxiv · Mar 15, 2022Microbiology

3D visualization of SARS-CoV-2 infection and receptor distribution in Syrian hamster lung lobes display distinct spatial arrangements

I. Tomris, K. M. Bouwman, Y. Adolfs, D. Noack, R. van der Woude, S. Herfst, G.-J. Boons, B. Haagmans, R. J. Pasterkamp, B. Rockx, R. P. de Vries

The paper uses 3D visualization to show that SARS-CoV-2 infection in Syrian hamster lungs occurs only where ACE2 and TMPRSS2 co-localize.

bioRxiv · Mar 24, 2021Microbiology

Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets

R. D. de Vries, K. S. Schmitz, F. T. Bovier, D. Noack, B. L. Haagmans, S. Biswas, B. Rockx, S. H. Gellman, C. A. Alabi, R. L. de Swart, A. MOSCONA, M. Porotto

bioRxiv · Nov 4, 2020Microbiology

SARS-CoV-2 neutralizing human antibodies protect against lower respiratory tract disease in a hamster model

B. L. Haagmans, D. Noack, N. M. A. Okba, W. LI, C. Wang, T. Bestebroer, R. de Vries, S. Herfst, D. de Meulder, P. van Run, M. M. Lamers, B. Rijnders, C. Rokx, F. J. M. van Kuppeveld, F. Grosveld, , B. Rockx

This study shows that high-dose convalescent plasma or monoclonal antibodies protect hamsters from SARS-CoV-2-induced lower respiratory disease, but lower doses are ineffective.

bioRxiv · Aug 24, 2020Microbiology